4x30: Difference between revisions
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==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution== | ==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution== | ||
<StructureSection load='4x30' size='340' side='right' caption='[[4x30]], [[Resolution|resolution]] 1.55Å' scene=''> | <StructureSection load='4x30' size='340' side='right'caption='[[4x30]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum. | [[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum. | ||
==See Also== | |||
*[[Serpin 3D structures|Serpin 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Qi, X]] | [[Category: Qi, X]] | ||
[[Category: Cation pi interaction]] | [[Category: Cation pi interaction]] | ||
Revision as of 10:59, 4 March 2020
Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolutionCrystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution
Structural highlights
Disease[THBG_HUMAN] Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:314200]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid. Function[THBG_HUMAN] Major thyroid hormone transport protein in serum. See Also |
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