4x30

Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolutionCrystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution

Structural highlights 4x30 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.55Å Ligands: , , , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease THBG_HUMAN Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:314200. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid. Function THBG_HUMAN Major thyroid hormone transport protein in serum. See Also Serpin 3D structures

spinqualitylabelsall models 4x30, resolution 1.55Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image