Phage integrase: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
Joel L. Sussman (talk | contribs)
ConfirmAccount, Editor, Journal, Mutation, Print3D, Tester, Bureaucrats, Administrators
7,920 edits
No edit summary
Michal Harel (talk | contribs)
31,761 edits
No edit summary
 
Line 4: Line 4:
*The biological assembly of Enterobacteria phage λ integrase is <scene name='44/443479/Cv/3'>homotetramer</scene>.
*The biological assembly of Enterobacteria phage λ integrase is <scene name='44/443479/Cv/3'>homotetramer</scene>.
</StructureSection>
</StructureSection>
== 3D Structures of phage integrase ==
== 3D Structures of phage integrase see [[Retroviral Integrase]]==


''Update June 2011''
[[3nrw]] – PIN/site-specific recombinase N-terminal – ''Haloarcula marismortui''<br />
[[3jtz]] – PIN arm-type binding domain – ''Yersinia pestis''<br />
[[3ju0]] – HPI PIN arm-type binding domain – ''Pectobacterium atrosepticum''<br />
[[2kkp]] – PIN SAM-like domain – ''Moorella thermoacetica'' – NMR<br />
[[2kkv]] – PIN fragment – ''Salmonella enterica'' – NMR<br />
[[2khq]] - PIN fragment – ''Staphylococcus saprophyticus'' – NMR<br />
[[2wcc]] – λPIN DBD+ DNA – Enterobacteria phage λ - NMR<br />
[[1kjk]] – λPIN N-terminal - NMR<br />
[[2oxo]], [[1z19]], [[1z1b]] - λPIN core binding domain + DNA<br />
[[1ae9]] - λPIN catalytic core domain (mutant) <br />
[[1z1g]] – λPIN + DNA (Holliday junction)<br />
[[1p7d]] – λPIN fragment + DNA <br />
[[3bvp]] – PIN catalytic core domain – Lactococcus phage TP101-1<br />
[[1aih]] - PIN catalytic core domain – Haemophilus phage HP1<br />
[[2khv]], [[2kj5]] – PIN residues 102-199 – ''Nitrosospira multiformis'' - NMR


== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 09:20, 5 September 2018


Phage integrase (PIN) mediates recombination between DNA recognition sequences - the phage attachment site attP and the bacterial attachment site attB[1]. The Tyrosine family PIN uses a catalytic tyrosine to mediate strand cleavage while the Serine family PIN uses a serine residue. The High-Pathogenicity Island (HPI) is a genomic island essential for virulence of the family of Enterobacteria.

  • The biological assembly of Enterobacteria phage λ integrase is .

Se-Met Enterobacteria phage λ integrase:DNA tetramer complex (Holiday Junction) 1z1g

Drag the structure with the mouse to rotate

3D Structures of phage integrase see Retroviral Integrase3D Structures of phage integrase see Retroviral Integrase

ReferencesReferences

  1. ↑ Groth AC, Calos MP. Phage integrases: biology and applications. J Mol Biol. 2004 Jan 16;335(3):667-78. PMID:14687564 doi:http://dx.doi.org/10.1016/S0022283603013561

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=Phage_integrase&oldid=2942753"