Phage integrase

Phage integrase (PIN) mediates recombination between DNA recognition sequences - the phage attachment site attP and the bacterial attachment site attB^[1]. The Tyrosine family PIN uses a catalytic tyrosine to mediate strand cleavage while the Serine family PIN uses a serine residue. The High-Pathogenicity Island (HPI) is a genomic island essential for virulence of the family of Enterobacteria.

The biological assembly of Enterobacteria phage λ integrase is .

Se-Met Enterobacteria phage λ integrase:DNA tetramer complex (Holiday Junction) 1z1g

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3D Structures of phage integrase see Retroviral Integrase3D Structures of phage integrase see Retroviral Integrase

ReferencesReferences

↑ Groth AC, Calos MP. Phage integrases: biology and applications. J Mol Biol. 2004 Jan 16;335(3):667-78. PMID:14687564 doi:http://dx.doi.org/10.1016/S0022283603013561

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Michal Harel, Alexander Berchansky, Joel L. Sussman

[1] Groth AC, Calos MP. Phage integrases: biology and applications. J Mol Biol. 2004 Jan 16;335(3):667-78. PMID:14687564 doi:http://dx.doi.org/10.1016/S0022283603013561

[1]

Phage integrase

3D Structures of phage integrase see Retroviral Integrase3D Structures of phage integrase see Retroviral Integrase

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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