Histone methyltransferase: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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 **[[2lxe]] – AtKHMT Suvr4 SET31 - NMR<br />
-*Histone-lysine N-methyltransferase binary complexes
+*Histone-lysine N-methyltransferase binary complexes with DNA
 **[[2kkf]] – hKHMT Hrx CxxC domain + DNA – NMR<br />
 **[[4nw3]] – hKHMT Mll CxxC domain + DNA <br />
-**[[4z4p]] – hKHMT Mll4 SET domain + SAH <br />
 **[[4pzi]] – hKHMT CxxC domain + DNA <br />
 **[[3q0b]], [[3q0c]], [[3q0d]], [[3q0f]] – hKHMT SRA domain + DNA <br />
+**[[5ei9]], [[5eh2]], [[5egb]] - hKHMT Prdm9 zinc finger domain + DNA<br />
+**[[4ygi]] – AtKHMT Suvh4 + DNA<br />
+*Histone-lysine N-methyltransferase binary complexes with methyl donor
+**[[4z4p]] – hKHMT Mll4 SET domain + SAH <br />
 **[[3qow]] – hKHMT + SAM <br />
 **[[4ynm]] – hKHMT Ash1L + SAM <br />
 **[[4ypu]], [[4ype]], [[4ypa]], [[4ynp]] – hKHMT Ash1L (mutant) + SAM <br />
-**[[4x8p]], [[4x8n]] – hKHMT Ash2L Spry domain + RBBP5 <br />
+**[[4h12]], [[5jle]] – hKHMT SETD2 catalytic domain + SAH <br />
+**[[3smt]] – hKHMT SETD3 + SAM <br />
+**[[4bup]], [[3ooi]] – hKHMT SET domain + SAM <br />
+**[[3qox]], [[3sx0]] – hKHMT + SAH <br />
+**[[2w5y]] – hKHMT Hrx methyltransferase domain + SAH <br />
+**[[3rib]] – hKHMT Smyd2 + SAH<br />
+**[[3s7j]], [[3tg4]] - hKHMT Smyd2 + SAM<br />
+**[[1mt6]] - hKHMT SET7/9 residues 58-337 + SAH<br />
+**[[1n6a]] – hKHMT SET7/9 SET domain + SAM<br />
+**[[1n6c]] – hKHMT SET7/9 residues 70-366 + SAM<br />
+*Histone-lysine N-methyltransferase binary complexes with inhibitor
 **[[5mw4]], [[5mw3]], [[5mvs]], [[5juw]], [[5dtr]], [[5dtq]], [[5dtm]], [[5dt2]], [[5dsx]], [[5dry]], [[5drt]], [[4wvl]] – hKHMT DOT1L + inhibitor <br />
 **[[4fmu]], [[5lt8]], [[5lt7]], [[5lt6]], [[5lsz]], [[5lsy]], [[5lsx]], [[5lsu]], [[5lss]] – hKHMT SETD2 + inhibitor <br />
-**[[4h12]], [[5jle]] – hKHMT SETD2 catalytic domain + SAH <br />
-**[[3smt]] – hKHMT SETD3 + SAM <br />
 **[[5th7]] – hKHMT SETD8 + inhibitor <br />
 **[[5t5g]] – hKHMT SETD8 (mutant) + inhibitor <br />
-**[[4bup]], [[3ooi]] – hKHMT SET domain + SAM <br />
 **[[5ke3]], [[5ke2]], [[5kco]], [[5kch]] - hKHMT SETDB1 tudor domain + inhibitor<br />
-**[[3qox]], [[3sx0]] – hKHMT + SAH <br />
 **[[3sr4]], [[3uwp]], [[4ek9]], [[4ekg]], [[4eki]], [[4eqz]], [[4er0]], [[4er3]], [[4er5]], [[4er6]], [[4er7]], [[4hra]] - hKHMT catalytic domain + inhibitor<br />
-**[[2w5y]] – hKHMT Hrx methyltransferase domain + SAH <br />
+**[[4wuy]] - hKHMT Smyd2 + inhibitor<br />
+**[[5cpr]] - hKHMT Suv420 SET domain + inhibitor<br />
+*Histone-lysine N-methyltransferase binary complexes with polypeptide
 **[[3f2k]] – hKHMT Setmar SET domain + LYFA peptide<br />
 **[[3sw9]], [[3swc]] – hKHMT SET domain + peptide<br />
@@ Line 94: / Line 111: @@
 **[[3b95]] - hKHMT ankyrin repeat domain + H3 peptide<br />
 **[[3lqi]], [[3lqj]] - hKHMT Mll1 3rd Phd finger and bromodomain + H3 peptide<br />
-**[[3rib]] – hKHMT Smyd2 + SAH<br />
-**[[3s7j]], [[3tg4]] - hKHMT Smyd2 + SAM<br />
-**[[4wuy]] - hKHMT Smyd2 + inhibitor<br />
 **[[5ex3]], [[5ex0]] - hKHMT Smyd3 + peptide<br />
-**[[1mt6]] - hKHMT SET7/9 residues 58-337 + SAH<br />
+**[[4l58]] - hKHMT PHD-type zinc finger domain + H3 peptide<br />
-**[[1n6a]] – hKHMT SET7/9 SET domain + SAM<br />
-**[[1n6c]] – hKHMT SET7/9 residues 70-366 + SAM<br />
+*Histone-lysine N-methyltransferase other binary complexes
 **[[3cbp]] - hKHMT SET7/9 SET domain + sinefungin<br />
 **[[3vuz]], [[3vv0]] - hKHMT SET7/9 SET domain + deoxyadenosine derivative<br />
-**[[4l58]] - hKHMT PHD-type zinc finger domain + H3 peptide<br />
+**[[4x8p]], [[4x8n]] – hKHMT Ash2L Spry domain + RBBP5 <br />
-**[[5ei9]], [[5eh2]], [[5egb]] - hKHMT Prdm9 zinc finger domain + DNA<br />
-**[[5cpr]] - hKHMT Suv420 SET domain + inhibitor<br />
-**[[4ygi]] – AtKHMT Suvh4 + DNA<br />
 *Histone-lysine N-methyltransferase ternary complex