BRCA: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
<StructureSection load='3coj' size=' | <StructureSection load='3coj' size='450' side='right' caption='Human BRCA1 BRCT1 and BRCT2 domains complex with phosphopeptide (PDB code [[3coj]]) ' scene='75/750267/Cv/3' pspeed='8'> | ||
== Function == | == Function == | ||
Line 8: | Line 8: | ||
== Structural highlights == | == Structural highlights == | ||
The phosphopeptide binds at the interface between the BRCT1 and BRCT2 domains. These domains contain most of the mutations seen in BRCA1<ref>PMID:18452305</ref>. | The <scene name='75/750267/Cv/1'>phosphopeptide binds at the interface between the BRCT1 and BRCT2 domains</scene>. These domains contain most of the mutations seen in BRCA1<ref>PMID:18452305</ref>. <scene name='75/750267/Cv/2'>Phosphoserine binding</scene>. | ||
</StructureSection> | </StructureSection> |