TRAIL: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1d0g' size='340' side='right' caption='Human TRAIL trimer residues 114-281 (grey, light green, yellow) complex with death receptor-5 extracellular domain (dark blue, dark green, olive), Zn+2 (grey) and Cl-1 (green) ions, [[1d0g]]' scene=''> | <StructureSection load='1d0g' size='340' side='right' caption='Human TRAIL trimer residues 114-281 (grey, light green, yellow) complex with death receptor-5 extracellular domain (dark blue, dark green, olive), Zn+2 (grey) and Cl-1 (green) ions, [[1d0g]]' scene=''> | ||
== Function == | == Function == | ||
'''TRAIL (TNF-related apoptosis-inducing ligand)''' functions as a ligand in the process of apoptosis<ref>PMID:15987601</ref>. TRAIL binds to death receptors DR4, DR5, DcR1 and DcR2. For details see [[Molecular Playground/TRAIL]]. | '''TRAIL (TNF-related apoptosis-inducing ligand)''' functions as a ligand in the process of apoptosis<ref>PMID:15987601</ref>. TRAIL binds to death receptors DR4, DR5, DcR1 and DcR2. For details see [[Molecular Playground/TRAIL]]. <scene name='48/480878/Cv/1'>TRAIL trimer residues complex with death receptor-5 extracellular domain</scene> ([[1d0g]]). | ||
== Disease == | == Disease == | ||