Pertussis toxin: Difference between revisions

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== Function ==
'''Pertussis toxin''' (PT) is produced by the bacterium ''Bordetella pertussis'' and is the cause of whooping cough<ref>PMID:15845471</ref>.  For additional details see [[Pertussis Toxin-ATP Complex]].<br />
'''Pertussis toxin''' (PT) is produced by the bacterium ''Bordetella pertussis'' and is the cause of whooping cough<ref>PMID:15845471</ref>.  For additional details see [[Pertussis Toxin-ATP Complex]].<br />
'''Pertactin''' is another toxin produced by ''Bordetella''.  For details see [[P.69 Pertactin Structure and Function]].
'''Pertactin''' is another toxin produced by ''Bordetella''.  For details see [[P.69 Pertactin Structure and Function]].


== Relevance ==
PT is associate with exacerbated host airway response during whooping cough infection and may inhibit host mechanisms of attenuating inflammation of the airways<ref>PMID:23027529</ref>.


== 3D Structures of Pertussis toxin ==
== 3D Structures of Pertussis toxin ==

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Jonathan Tringali, Michal Harel