Interleukin-1 receptor-associated kinase: Difference between revisions
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m Interleukin-1 receptor-associated kinase 4 moved to Interleukin-1 receptor-associated kinase: requested by Editor |
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<StructureSection load='2a9i' size='340' side='right' caption='Mouse IRAK4 death domain complex with Mn+2 ion , [[2a9i]]' scene=''> | |||
== Function == | == Function == | ||
'''Interleukin-1 receptor-associated kinase''' (IRAK) is a kinase involved in signaling innate immune responses from Toll-like receptors and interleukin-1 receptor-related proteins<ref>PMID:8599092</ref>. | '''Interleukin-1 receptor-associated kinase''' (IRAK) is a kinase involved in signaling innate immune responses from Toll-like receptors and interleukin-1 receptor-related proteins<ref>PMID:8599092</ref>. | ||
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== Disease == | == Disease == | ||
IRAK4 deficiency is a disorder which causes recurrent bacterial infections. | IRAK4 deficiency is a disorder which causes recurrent bacterial infections. | ||
</StructureSection> | |||
==3D structures of IRAK4== | ==3D structures of IRAK4== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
Revision as of 11:42, 22 June 2017
FunctionInterleukin-1 receptor-associated kinase (IRAK) is a kinase involved in signaling innate immune responses from Toll-like receptors and interleukin-1 receptor-related proteins[1]. RelevanceIRAK4 is involved in early recognition of pathogens and the initiation of inflammation when fighting infection. DiseaseIRAK4 deficiency is a disorder which causes recurrent bacterial infections. |
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3D structures of IRAK43D structures of IRAK4
Updated on 22-June-2017