2qth: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 1: Line 1:
==Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP==
==Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP==
<StructureSection load='2qth' size='340' side='right' caption='[[2qth]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2qth' size='340' side='right' caption='[[2qth]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Line 5: Line 6:
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qtf|2qtf]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qtf|2qtf]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hflX, SSO0269 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Sulfolobus solfataricus P2])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hflX, SSO0269 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 Sulfolobus solfataricus P2])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qth OCA], [http://pdbe.org/2qth PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qth RCSB], [http://www.ebi.ac.uk/pdbsum/2qth PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qth OCA], [http://pdbe.org/2qth PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qth RCSB], [http://www.ebi.ac.uk/pdbsum/2qth PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qth ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
Line 20: Line 21:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qth ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qth ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[GTP-binding protein|GTP-binding protein]]
== References ==
== References ==
<references/>
<references/>

Revision as of 10:35, 25 October 2017

Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDPCrystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP

Structural highlights

2qth is a 1 chain structure with sequence from Sulfolobus solfataricus p2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:hflX, SSO0269 (Sulfolobus solfataricus P2)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[HFLX_SULSO] GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Specific for GTP.[HAMAP-Rule:MF_00900][1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Wu H, Sun L, Blombach F, Brouns SJ, Snijders AP, Lorenzen K, van den Heuvel RH, Heck AJ, Fu S, Li X, Zhang XC, Rao Z, van der Oost J. Structure of the ribosome associating GTPase HflX. Proteins. 2010 Feb 15;78(3):705-13. doi: 10.1002/prot.22599. PMID:19787775 doi:http://dx.doi.org/10.1002/prot.22599
  2. ↑ Blombach F, Launay H, Zorraquino V, Swarts DC, Cabrita LD, Benelli D, Christodoulou J, Londei P, van der Oost J. An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states. J Bacteriol. 2011 Jun;193(11):2861-7. doi: 10.1128/JB.01552-10. Epub 2011 Apr 8. PMID:21478358 doi:http://dx.doi.org/10.1128/JB.01552-10

2qth, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2qth&oldid=2795471"