2qtf

Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricusCrystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus

Structural highlights

2qtf is a 1 chain structure with sequence from Saccharolobus solfataricus P2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HFLX_SACS2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Specific for GTP.[HAMAP-Rule:MF_00900]^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Wu H, Sun L, Blombach F, Brouns SJ, Snijders AP, Lorenzen K, van den Heuvel RH, Heck AJ, Fu S, Li X, Zhang XC, Rao Z, van der Oost J. Structure of the ribosome associating GTPase HflX. Proteins. 2010 Feb 15;78(3):705-13. doi: 10.1002/prot.22599. PMID:19787775 doi:http://dx.doi.org/10.1002/prot.22599
↑ Blombach F, Launay H, Zorraquino V, Swarts DC, Cabrita LD, Benelli D, Christodoulou J, Londei P, van der Oost J. An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states. J Bacteriol. 2011 Jun;193(11):2861-7. doi: 10.1128/JB.01552-10. Epub 2011 Apr 8. PMID:21478358 doi:http://dx.doi.org/10.1128/JB.01552-10

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OCA

[1] Wu H, Sun L, Blombach F, Brouns SJ, Snijders AP, Lorenzen K, van den Heuvel RH, Heck AJ, Fu S, Li X, Zhang XC, Rao Z, van der Oost J. Structure of the ribosome associating GTPase HflX. Proteins. 2010 Feb 15;78(3):705-13. doi: 10.1002/prot.22599. PMID:19787775 doi:http://dx.doi.org/10.1002/prot.22599

[2] Blombach F, Launay H, Zorraquino V, Swarts DC, Cabrita LD, Benelli D, Christodoulou J, Londei P, van der Oost J. An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states. J Bacteriol. 2011 Jun;193(11):2861-7. doi: 10.1128/JB.01552-10. Epub 2011 Apr 8. PMID:21478358 doi:http://dx.doi.org/10.1128/JB.01552-10

[1]

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2qtf

Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricusCrystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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2qtf

Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricusCrystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus

Structural highlights

Function

Evolutionary Conservation

See Also

References

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