Arrestin: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='2wtr' size='340' side='right' caption='Bovine arrestin-2 (PDB code 2wtr)' scene=''> '''Arrestin''' (ARR) is a ubiquitous protein which binds to the G protein-c... |
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<StructureSection load='2wtr' size='340' side='right' caption='Bovine arrestin-2 complex with Ba+2 ions (PDB code [[2wtr]])' scene=''> | |||
<StructureSection load='2wtr' size='340' side='right' caption='Bovine arrestin-2 (PDB code [[2wtr]])' scene=''> | |||
'''Arrestin''' (ARR) is a ubiquitous protein which binds to the G protein-coupled receptor after its phosphorylation. ARR binding blocks further G protein-mediated signaling and redirects signaling to alternative non-G protein-independent pathways. Hence, ARR are versatile adaptor molecules which can also activate signaling cascades and are involved in nuclear functions. | '''Arrestin''' (ARR) is a ubiquitous protein which binds to the G protein-coupled receptor after its phosphorylation. ARR binding blocks further G protein-mediated signaling and redirects signaling to alternative non-G protein-independent pathways. Hence, ARR are versatile adaptor molecules which can also activate signaling cascades and are involved in nuclear functions. | ||
Revision as of 11:25, 7 July 2015
Arrestin (ARR) is a ubiquitous protein which binds to the G protein-coupled receptor after its phosphorylation. ARR binding blocks further G protein-mediated signaling and redirects signaling to alternative non-G protein-independent pathways. Hence, ARR are versatile adaptor molecules which can also activate signaling cascades and are involved in nuclear functions. FunctionDiseaseRelevanceStructural highlights |
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3D Structures of arrestin3D Structures of arrestin
Updated on 07-July-2015