1ayr

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ARRESTIN FROM BOVINE ROD OUTER SEGMENTSARRESTIN FROM BOVINE ROD OUTER SEGMENTS

Structural highlights

1ayr is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

ARRS_BOVIN Note=S-antigen induces autoimmune uveitis.

Function

ARRS_BOVIN Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ayr, resolution 3.30Å

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OCA