Leukocyte immunoglobulin-like receptor: Difference between revisions

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<StructureSection load='1p7q' size='350' side='right' caption='Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (yellow) complex with class I MHC (grey), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry [[1p7q]])' scene=''>
<StructureSection load='1p7q' size='350' side='right' caption='Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (yellow) complex with class I MHC (grey), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry [[1p7q]])' scene=''>
    
    
'''Leukocyte immunoglobulin-like receptors''' (LIR) or '''CD85''' have extracellular immunoglobulin domains.  LIR modulates a variety of immune cells.  LIR interacts with class I MHC molecules.
'''Leukocyte immunoglobulin-like receptors''' (LIR) or '''CD85''' have extracellular immunoglobulin domains.  LIR modulates a variety of immune cells.  LIR interacts with class I MHC molecules<ref>PMID:19548123</ref>.
</StructureSection>
</StructureSection>


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**[[3d2u]] – hLIR ligand-binding domain + herpesvirus UL18 + β-2 microglobulin +  actin peptide<br />
**[[3d2u]] – hLIR ligand-binding domain + herpesvirus UL18 + β-2 microglobulin +  actin peptide<br />
}}
}}
== References ==
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:29, 11 April 2016


Leukocyte immunoglobulin-like receptors (LIR) or CD85 have extracellular immunoglobulin domains. LIR modulates a variety of immune cells. LIR interacts with class I MHC molecules[1].

Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (yellow) complex with class I MHC (grey), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry 1p7q)

Drag the structure with the mouse to rotate

3D structures of leukocyte immunoglobulin-like receptor3D structures of leukocyte immunoglobulin-like receptor

Updated on 11-April-2016

ReferencesReferences

  1. Thomas R, Matthias T, Witte T. Leukocyte immunoglobulin-like receptors as new players in autoimmunity. Clin Rev Allergy Immunol. 2010 Apr;38(2-3):159-62. doi:, 10.1007/s12016-009-8148-8. PMID:19548123 doi:http://dx.doi.org/10.1007/s12016-009-8148-8

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman