CD2-associated protein

<StructureSection load='2j6o' size='350' side='right' caption='Structure of human CD2AP SH3 domain 1 (grey) complex with E3 ubiquitin ligase peptide (pink) (PDB entry 2j6o)' scene=>

CD2-associated protein (CD2AP) called also CMS, is a scaffolding protein which regulates actin cytoskeleton. CD2AP SH3 domain interacts with actin and a variety of membrane proteins. CD2AP contains in its N-terminal 3 SH3 domains followed by a proline-rich region.

3D structures of CD2-associated protein3D structures of CD2-associated protein

Updated on 20-November-2014

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• CD2AP SH3 domain 1
  • 2j6k – hCD2AP – human
    
  • 2krm – mCD2AP – mouse - NMR
    
  • 2j6f – hCD2AP + E3 ubiquitin protein ligase peptide
    
  • 2j6o, 2j7i – hCD2AP + CD2 peptide
    
  • 2mcn - mCD2AP + ubiquitin
    
• CD2AP SH3 domain 2
  • 2fei – hCD2AP – NMR
    
  • 3u23 - hCD2AP + RIN3 proline-rich peptide
    
• CD2AP SH3 domain 3
  • 2jte, 2kro – mCD2AP - NMR
    
  • 2lz6 – hCD2AP + ubiquitin - NMR
    
• CD2AP proline-rich domain
  • 3lk4, 3aa6 – hCD2AP + CapZ