3o61: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3o61]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O61 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O61 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3o61]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O61 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O61 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDD:GUANOSINE-5-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDD:GUANOSINE-5-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o52|3o52]], [[3o69|3o69]], [[3o6z|3o6z]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o52|3o52]], [[3o69|3o69]], [[3o6z|3o6z]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2467, JW2451, nudK, yffH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2467, JW2451, nudK, yffH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o61 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o61 RCSB], [http://www.ebi.ac.uk/pdbsum/3o61 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o61 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o61 RCSB], [http://www.ebi.ac.uk/pdbsum/3o61 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NUDK_ECOLI NUDK_ECOLI]] Catalyzes the hydrolysis of GDP-mannose. Can also use other substrates, catalyzing the hydrolysis of the pyrophosphate bond, releasing a nucleoside monophosphate and a phosphorylated moiety, depending on the substrate.<ref>PMID:16766526</ref> 
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.,Boto AN, Xu W, Jakoncic J, Pannuri A, Romeo T, Bessman MJ, Gabelli SB, Amzel LM Proteins. 2011 Aug;79(8):2455-66. doi: 10.1002/prot.23069. Epub 2011 Jun, 2. PMID:21638333<ref>PMID:21638333</ref>
Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.,Boto AN, Xu W, Jakoncic J, Pannuri A, Romeo T, Bessman MJ, Gabelli SB, Amzel LM Proteins. 2011 Aug;79(8):2455-66. doi: 10.1002/prot.23069. Epub 2011 Jun, 2. PMID:21638333<ref>PMID:21638333</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Amzel, L M.]]
[[Category: Amzel, L M]]
[[Category: Boto, A N.]]
[[Category: Boto, A N]]
[[Category: Gabelli, S B.]]
[[Category: Gabelli, S B]]
[[Category: Biofilm]]
[[Category: Biofilm]]
[[Category: Gdp_mannose]]
[[Category: Gdp_mannose]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Nudix]]
[[Category: Nudix]]

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