Mandelate racemase: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


[[2mnr]] – PpMAR  – ''Pseudomonas putida''<br />
*'''mandelate racemase'''
[[2hzg]] – MAR – ''Rhodobacter sphaeroides''<br />
[[2og9]], [[3bjs]] – MAR – ''Polaromonas''<br />
[[2pmq]], [[2rdx]], [[3u4f]], [[3fvd]], [[2qdd]] – MAR – ''Roseovarius''<br />
[[2qde]] – MAR – ''Azoarcus''<br />
[[3ik4]] – MAR – ''Herpetosiphon aurantiacus''<br />
[[3mqt]], [[3sjn]] – MAR – ''Shewanella pealeana''<br />
[[3n4e]], [[4dwd]] – MAR – ''Paracoccus denitrificans''<br />
[[3n4f ]]– GeMAR – ''Geobacillus''<br />
[[3msy]], [[3no1]] – MAR – ''Marine actinobacterium''<br />
[[3n6h]], [[3n6j]] – MAR – ''Actinobacillus succinogenes''<br />
[[3ddm]] - BbMAR (mutant) – ''Bordetella bronchiseptica''<br />
[[3h12]] – BbMAR<br />
[[3ssz]] – MAR – ''Rhodobacteraceae bacterium''<br />
[[3t4w]] – MAR – ''Sulfitobacter''<br />
[[3t8q]] – MAR – ''Hoeflea phototrophica''<br />
[[3u9i]] – MAR – ''Roseiflexus''<br />
[[4dx3]], [[4e8g]], [[3tj4]], [[3tji]] – AtMAR – ''Agrobacterium tumefaciens''<br />
[[3s47]] – MAR – ''Clostridium beijerincki''<br />
[[4dhg]], [[3vc5]], [[3vc6]] – MAR – ''Thermobispora bispora''<br />
[[4e4f]] – MAR – ''Pectobacterium carotovorum''<br />
[[3thu]] – MAR – ''Sphingomonas''<br />
[[3toy]] – BrMAR – ''Bradyrhizobium''<br />
[[3ugv]] – MAR – ''alpha proteobacterium''<br />
[[2pod]] – MAR – ''Burkholderia pseudomallei''<br />
[[3dfh]] - VbMAR – ''Vibrionales bacterium''<br />


===Mandelate racemase binary complex===
**[[2mnr]] – PpMAR  – ''Pseudomonas putida''<br />
**[[2hzg]] – MAR – ''Rhodobacter sphaeroides''<br />
**[[2og9]], [[3bjs]] – MAR – ''Polaromonas''<br />
**[[2pmq]], [[2rdx]], [[3u4f]], [[3fvd]], [[2qdd]] – MAR – ''Roseovarius''<br />
**[[2qde]] – MAR – ''Azoarcus''<br />
**[[3ik4]] – MAR – ''Herpetosiphon aurantiacus''<br />
**[[3mqt]], [[3sjn]] – MAR – ''Shewanella pealeana''<br />
**[[3n4e]], [[4dwd]] – MAR – ''Paracoccus denitrificans''<br />
**[[3n4f]] – GeMAR – ''Geobacillus''<br />
**[[3msy]], [[3no1]] – MAR – ''Marine actinobacterium''<br />
**[[3n6h]], [[3n6j]] – MAR – ''Actinobacillus succinogenes''<br />
**[[3ddm]] - BbMAR (mutant) – ''Bordetella bronchiseptica''<br />
**[[3h12]] – BbMAR<br />
**[[3ssz]] – MAR – ''Rhodobacteraceae bacterium''<br />
**[[3t4w]] – MAR – ''Sulfitobacter''<br />
**[[3t8q]] – MAR – ''Hoeflea phototrophica''<br />
**[[3u9i]] – MAR – ''Roseiflexus''<br />
**[[4dx3]], [[4e8g]], [[3tj4]], [[3tji]] – AtMAR – ''Agrobacterium tumefaciens''<br />
**[[3s47]] – MAR – ''Clostridium beijerincki''<br />
**[[4dhg]], [[3vc5]], [[3vc6]] – MAR – ''Thermobispora bispora''<br />
**[[4e4f]] – MAR – ''Pectobacterium carotovorum''<br />
**[[3thu]] – MAR – ''Sphingomonas''<br />
**[[3toy]] – BrMAR – ''Bradyrhizobium''<br />
**[[3ugv]] – MAR – ''alpha proteobacterium''<br />
**[[2pod]] – MAR – ''Burkholderia pseudomallei''<br />
**[[3dfh]] - VbMAR – ''Vibrionales bacterium''<br />


[[1mns]], [[1mdr]] – PpMAR + alpha phenyl glycidate <br />
*Mandelate racemase binary complex
[[3ops]] – GeMAR + lactate<br />
[[1mra]], [[1dtn]] – PpMAR (mutant) + atrolactate<br />
[[1mdl]] - PpMAR (mutant) + mandelate<br />
[[4hnc]] - PpMAR (mutant) + benzilic acid<br />
[[4m6u]] - PpMAR + tartronic acid<br />
[[4fp1]] – PpMAR + inhibitor<br />
[[3tte]] - BrMAR + mandelate<br />
[[3uxk]], [[3uxl]] – PpMAR + intermediate analog<br />
[[3sbf]] – VbMAR (mutant) + arabinonate <br />
[[3r25]] – VbMAR + glycerol<br />
[[4gfi]] – AtMAR + dipeptide epimerase<br />
[[4h19]] – AtMAR + ribonohydroxamate<br />


**[[1mns]], [[1mdr]] – PpMAR + alpha phenyl glycidate <br />
**[[3ops]] – GeMAR + lactate<br />
**[[1mra]], [[1dtn]] – PpMAR (mutant) + atrolactate<br />
**[[1mdl]] - PpMAR (mutant) + mandelate<br />
**[[4hnc]] - PpMAR (mutant) + benzilic acid<br />
**[[4m6u]] - PpMAR + tartronic acid<br />
**[[4fp1]] – PpMAR + inhibitor<br />
**[[3tte]] - BrMAR + mandelate<br />
**[[3uxk]], [[3uxl]] – PpMAR + intermediate analog<br />
**[[3sbf]] – VbMAR (mutant) + arabinonate <br />
**[[3r25]] – VbMAR + glycerol<br />
**[[4gfi]] – AtMAR + dipeptide epimerase<br />
**[[4h19]] – AtMAR + ribonohydroxamate<br />
}}
   
   



Revision as of 10:51, 1 December 2014


Mandelate rasemase (MAR) catalyzes the interconversion of enantiomers of mandelate (S to R). MAR is Mg-dependent. MAR can racemize other alpha-hydroxy carbonyl compounds. MAR is involved in aromatic acids catabolism.

3D structures of mandelate racemase

Updated on 04-June-2025

{{#tree:id=OrganizedByTopic|openlevels=0|

  • mandelate racemase
    • 2mnr – PpMAR – Pseudomonas putida
    • 2hzg – MAR – Rhodobacter sphaeroides
    • 2og9, 3bjs – MAR – Polaromonas
    • 2pmq, 2rdx, 3u4f, 3fvd, 2qdd – MAR – Roseovarius
    • 2qde – MAR – Azoarcus
    • 3ik4 – MAR – Herpetosiphon aurantiacus
    • 3mqt, 3sjn – MAR – Shewanella pealeana
    • 3n4e, 4dwd – MAR – Paracoccus denitrificans
    • 3n4f – GeMAR – Geobacillus
    • 3msy, 3no1 – MAR – Marine actinobacterium
    • 3n6h, 3n6j – MAR – Actinobacillus succinogenes
    • 3ddm - BbMAR (mutant) – Bordetella bronchiseptica
    • 3h12 – BbMAR
    • 3ssz – MAR – Rhodobacteraceae bacterium
    • 3t4w – MAR – Sulfitobacter
    • 3t8q – MAR – Hoeflea phototrophica
    • 3u9i – MAR – Roseiflexus
    • 4dx3, 4e8g, 3tj4, 3tji – AtMAR – Agrobacterium tumefaciens
    • 3s47 – MAR – Clostridium beijerincki
    • 4dhg, 3vc5, 3vc6 – MAR – Thermobispora bispora
    • 4e4f – MAR – Pectobacterium carotovorum
    • 3thu – MAR – Sphingomonas
    • 3toy – BrMAR – Bradyrhizobium
    • 3ugv – MAR – alpha proteobacterium
    • 2pod – MAR – Burkholderia pseudomallei
    • 3dfh - VbMAR – Vibrionales bacterium
  • Mandelate racemase binary complex
    • 1mns, 1mdr – PpMAR + alpha phenyl glycidate
    • 3ops – GeMAR + lactate
    • 1mra, 1dtn – PpMAR (mutant) + atrolactate
    • 1mdl - PpMAR (mutant) + mandelate
    • 4hnc - PpMAR (mutant) + benzilic acid
    • 4m6u - PpMAR + tartronic acid
    • 4fp1 – PpMAR + inhibitor
    • 3tte - BrMAR + mandelate
    • 3uxk, 3uxl – PpMAR + intermediate analog
    • 3sbf – VbMAR (mutant) + arabinonate
    • 3r25 – VbMAR + glycerol
    • 4gfi – AtMAR + dipeptide epimerase
    • 4h19 – AtMAR + ribonohydroxamate

}}




Structure of mandelate racemase dimer complex with mandelate, glycerol, formate, Mg+2 ion (green) (PDB entry 3tte)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Karsten Theis