BAG protein: Difference between revisions
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===BAG-1=== | |||
[[1i6z]] – mBAG-1 BAG domain - mouse<br /> | [[1i6z]] – mBAG-1 BAG domain - mouse<br /> | ||
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[[1wxv]] – hBAG-1 BAG domain – human - NMR<br /> | [[1wxv]] – hBAG-1 BAG domain – human - NMR<br /> | ||
''BAG-1 complex with HSC70'' | |||
[[3fzf]] – hBAG-1 BAG domain + HSC70 ATPase domain + ATP<br /> | [[3fzf]] – hBAG-1 BAG domain + HSC70 ATPase domain + ATP<br /> | ||
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[[1hx1]] – BAG-1 BAG domain + HSC70 ATPase domain - bovine<br /> | [[1hx1]] – BAG-1 BAG domain + HSC70 ATPase domain - bovine<br /> | ||
===BAG-2=== | |||
[[3d0t]] – mBAG-2 BAG domain <br /> | [[3d0t]] – mBAG-2 BAG domain <br /> | ||
''BAG-2 complex with HSC70'' | |||
[[3cqx]] – mBAG-2 BAG domain + HSC70 ATPase domain <br /> | [[3cqx]] – mBAG-2 BAG domain + HSC70 ATPase domain <br /> | ||
===BAG-4=== | |||
[[1m62]], [[1m7k]] – hBAG-4 BAG domain - NMR<br /> | [[1m62]], [[1m7k]] – hBAG-4 BAG domain - NMR<br /> | ||
===BAG-5=== | |||
[[1ugo]] – mBAG-5 BAG domain - NMR<br /> | [[1ugo]] – mBAG-5 BAG domain - NMR<br /> | ||
[[2d9d]] – hBAG-5 BAG domain - NMR<br /> | [[2d9d]] – hBAG-5 BAG domain - NMR<br /> | ||
''BAG-5 complex with HSC70'' | |||
[[3a8y]] – hBAG-5 BAG domain + HSC70 ATPase domain <br /> | [[3a8y]] – hBAG-5 BAG domain + HSC70 ATPase domain <br /> | ||
===BAG-6=== | |||
[[4eew]] – hBAG-6 UBL domain <br /> | [[4eew]] – hBAG-6 UBL domain <br /> | ||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||
Revision as of 14:01, 14 August 2014
<StructureSection load='3fzf' size='350' side='right' caption='Structure of human BAG-1 BAG domain (green) complex with HSC70 ATPase domain (grey) and ATP (PDB entry 3fzf)' scene=>
The BAG family proteins (Bcl-2 associated athanogenes) perform diverse functions. They contain a common BAG domain ca. 45 amino acid long near the C terminal which is conserved. BAG-1, BAG-2, BAG-4, BAG-5 or BAG family molecular chaperone regulator inhibit the chaperone function of HSC70 and have anti-apoptotic function.
3D structures of BAG family proteins3D structures of BAG family proteins
Updated on 14-August-2014
BAG-1BAG-1
1i6z – mBAG-1 BAG domain - mouse
2lwp – mBAG-1 BAG domain - NMR
1t7s – BAG-1 BAG domain – Caenorhabditis elegans
4hwc – AtBAG-1 BAG domain – Arabidopsis thaliana
1wxv – hBAG-1 BAG domain – human - NMR
BAG-1 complex with HSC70
3fzf – hBAG-1 BAG domain + HSC70 ATPase domain + ATP
3fzh, 3fzk, 3fzl, 3fzm, 3ldq, 3m3z – hBAG-1 BAG domain + HSC70 ATPase domain + inhibitor
4hwi – AtBAG-1 BAG domain + HSC70 ATPase domain
1hx1 – BAG-1 BAG domain + HSC70 ATPase domain - bovine
BAG-2BAG-2
3d0t – mBAG-2 BAG domain
BAG-2 complex with HSC70
3cqx – mBAG-2 BAG domain + HSC70 ATPase domain
BAG-4BAG-4
1m62, 1m7k – hBAG-4 BAG domain - NMR
BAG-5BAG-5
1ugo – mBAG-5 BAG domain - NMR
2d9d – hBAG-5 BAG domain - NMR
BAG-5 complex with HSC70
3a8y – hBAG-5 BAG domain + HSC70 ATPase domain
BAG-6BAG-6
4eew – hBAG-6 UBL domain