4gzd: Difference between revisions
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{{STRUCTURE_4gzd| PDB=4gzd | SCENE= }} | |||
===Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q=== | |||
{{ABSTRACT_PUBMED_23553749}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST]] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref> | |||
==About this Structure== | |||
[[4gzd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZD OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae s288c]] | |||
[[Category: Costakes, G T.]] | |||
[[Category: Stauffacher, C V.]] | |||
[[Category: Endocytosis]] | |||
[[Category: Enth]] | |||
[[Category: Lipid binding protein]] | |||
Revision as of 10:22, 16 May 2013
Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118QCrystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q
Template:ABSTRACT PUBMED 23553749
FunctionFunction
[ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.[1]
About this StructureAbout this Structure
4gzd is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383