4gzd

Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118QCrystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q

Structural highlights

4gzd is a 1 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.75Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ENT2_YEAST Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.^[1]

References

↑ Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383

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OCA

[1] Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383

[1]

4gzd

Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118QCrystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q

Structural highlights

Function

See Also

References

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4gzd

Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118QCrystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q

Structural highlights

Function

See Also

References

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