2g71: Difference between revisions

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[[Image:2g71.png|left|200px]]
{{STRUCTURE_2g71|  PDB=2g71  |  SCENE=  }}  
{{STRUCTURE_2g71|  PDB=2g71  |  SCENE=  }}  
===Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy===
===Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy===
{{ABSTRACT_PUBMED_17845018}}


{{ABSTRACT_PUBMED_17845018}}
==Function==
[[http://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN]] Converts noradrenaline to adrenaline.


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:017845018</ref><references group="xtra"/>
<ref group="xtra">PMID:017845018</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]

Revision as of 09:19, 2 October 2013

Template:STRUCTURE 2g71

Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcyStructure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy

Template:ABSTRACT PUBMED 17845018

FunctionFunction

[PNMT_HUMAN] Converts noradrenaline to adrenaline.

About this StructureAbout this Structure

2g71 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385

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OCA