1agn: Difference between revisions

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[[Image:1agn.gif|left|200px]]<br /><applet load="1agn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1agn.gif|left|200px]]
caption="1agn, resolution 3.&Aring;" />
 
'''X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE'''<br />
{{Structure
|PDB= 1agn |SIZE=350|CAPTION= <scene name='initialview01'>1agn</scene>, resolution 3.&Aring;
|SITE= <scene name='pdbsite=ZN1:Zn+Binding+Site'>ZN1</scene>, <scene name='pdbsite=ZN2:Zn+Binding+Site'>ZN2</scene>, <scene name='pdbsite=ZN3:Zn+Binding+Site'>ZN3</scene>, <scene name='pdbsite=ZN4:Zn+Binding+Site'>ZN4</scene>, <scene name='pdbsite=ZN5:Zn+Binding+Site'>ZN5</scene>, <scene name='pdbsite=ZN6:Zn+Binding+Site'>ZN6</scene>, <scene name='pdbsite=ZN7:Zn+Binding+Site'>ZN7</scene> and <scene name='pdbsite=ZN8:Zn+Binding+Site'>ZN8</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]
|GENE= HUMAN SIGMA CDNA (ADH7) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1AGN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1AGN with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb13_1.html Alcohol Dehydrogenase]]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Known structural/functional Sites: <scene name='pdbsite=ZN1:Zn+Binding+Site'>ZN1</scene>, <scene name='pdbsite=ZN2:Zn+Binding+Site'>ZN2</scene>, <scene name='pdbsite=ZN3:Zn+Binding+Site'>ZN3</scene>, <scene name='pdbsite=ZN4:Zn+Binding+Site'>ZN4</scene>, <scene name='pdbsite=ZN5:Zn+Binding+Site'>ZN5</scene>, <scene name='pdbsite=ZN6:Zn+Binding+Site'>ZN6</scene>, <scene name='pdbsite=ZN7:Zn+Binding+Site'>ZN7</scene> and <scene name='pdbsite=ZN8:Zn+Binding+Site'>ZN8</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AGN OCA].  
1AGN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1AGN with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb13_1.html Alcohol Dehydrogenase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AGN OCA].  


==Reference==
==Reference==
X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity., Xie P, Parsons SH, Speckhard DC, Bosron WF, Hurley TD, J Biol Chem. 1997 Jul 25;272(30):18558-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9228021 9228021]
X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity., Xie P, Parsons SH, Speckhard DC, Bosron WF, Hurley TD, J Biol Chem. 1997 Jul 25;272(30):18558-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9228021 9228021]
[[Category: Alcohol Dehydrogenase]]
[[Category: Alcohol Dehydrogenase]]
[[Category: Alcohol dehydrogenase]]
[[Category: Alcohol dehydrogenase]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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