1eat: Difference between revisions
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[[Image:1eat.png|left|200px]] | [[Image:1eat.png|left|200px]] | ||
{{STRUCTURE_1eat| PDB=1eat | SCENE= }} | {{STRUCTURE_1eat| PDB=1eat | SCENE= }} | ||
===NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY ACTIVE 5-AMINO-PYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYLKETONES=== | ===NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY ACTIVE 5-AMINO-PYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYLKETONES=== | ||
{{ABSTRACT_PUBMED_7837246}} | {{ABSTRACT_PUBMED_7837246}} | ||
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==See Also== | ==See Also== | ||
*[[Elastase]] | *[[Elastase|Elastase]] | ||
==Reference== | ==Reference== | ||
Revision as of 21:01, 26 July 2012
NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY ACTIVE 5-AMINO-PYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYLKETONESNONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY ACTIVE 5-AMINO-PYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYLKETONES
Template:ABSTRACT PUBMED 7837246
About this StructureAbout this Structure
1eat is a 1 chain structure of Elastase with sequence from Sus scrofa. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Veale CA, Bernstein PR, Bryant C, Ceccarelli C, Damewood JR Jr, Earley R, Feeney SW, Gomes B, Kosmider BJ, Steelman GB, et al.. Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and X-ray crystallography of a series of orally active 5-aminopyrimidin-6-one-containing trifluoromethyl ketones. J Med Chem. 1995 Jan 6;38(1):98-108. PMID:7837246