3g0e: Difference between revisions

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[[Image:3g0e.png|left|200px]]
[[Image:3g0e.png|left|200px]]


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{{STRUCTURE_3g0e|  PDB=3g0e  |  SCENE=  }}  
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===KIT kinase domain in complex with sunitinib===
===KIT kinase domain in complex with sunitinib===


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{{ABSTRACT_PUBMED_19164557}}
{{ABSTRACT_PUBMED_19164557}}


==About this Structure==
==About this Structure==
[[3g0e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0E OCA].  
[[3g0e]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0E OCA].  


==See Also==
==See Also==
*[[Sunitinib]]
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]
*[[Sunitinib|Sunitinib]]


==Reference==
==Reference==
<ref group="xtra">PMID:19164557</ref><references group="xtra"/>
<ref group="xtra">PMID:019164557</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
[[Category: Receptor]]
[[Category: Receptor]]

Revision as of 19:46, 26 July 2012

File:3g0e.png

Template:STRUCTURE 3g0e

KIT kinase domain in complex with sunitinibKIT kinase domain in complex with sunitinib

Template:ABSTRACT PUBMED 19164557

About this StructureAbout this Structure

3g0e is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Gajiwala KS, Wu JC, Christensen J, Deshmukh GD, Diehl W, Dinitto JP, English JM, Greig MJ, He YA, Jacques SL, Lunney EA, McTigue M, Molina D, Quenzer T, Wells PA, Yu X, Zhang Y, Zou A, Emmett MR, Marshall AG, Zhang HM, Demetri GD. KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1542-7. Epub 2009 Jan 21. PMID:19164557

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