1x8x: Difference between revisions

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[[Image:1x8x.png|left|200px]]


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==Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine==
The line below this paragraph, containing "STRUCTURE_1x8x", creates the "Structure Box" on the page.
<StructureSection load='1x8x' size='340' side='right'caption='[[1x8x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1x8x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X8X FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
{{STRUCTURE_1x8x| PDB=1x8x |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x8x OCA], [https://pdbe.org/1x8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x8x RCSB], [https://www.ebi.ac.uk/pdbsum/1x8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x8x ProSAT], [https://www.topsan.org/Proteins/RSGI/1x8x TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYY_ECOLI SYY_ECOLI] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02006]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x8x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x8x ConSurf].
<div style="clear:both"></div>


===Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine===
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_15663931}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15663931 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15663931}}
 
==About this Structure==
1X8X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X8X OCA].
 
==Reference==
Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase., Kobayashi T, Takimura T, Sekine R, Kelly VP, Kamata K, Sakamoto K, Nishimura S, Yokoyama S, J Mol Biol. 2005 Feb 11;346(1):105-17. Epub 2004 Dec 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15663931 15663931]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Kamata K]]
[[Category: Kamata, K.]]
[[Category: Kelly VP]]
[[Category: Kelly, V P.]]
[[Category: Kobayashi T]]
[[Category: Kobayashi, T.]]
[[Category: Nishimura S]]
[[Category: Nishimura, S.]]
[[Category: Sakamoto K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sekine R]]
[[Category: Sakamoto, K.]]
[[Category: Takimura T]]
[[Category: Sekine, R.]]
[[Category: Yokoyama S]]
[[Category: Takimura, T.]]
[[Category: Yokoyama, S.]]
[[Category: Ligase]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:47:21 2008''

Latest revision as of 16:36, 13 March 2024

Tyrosyl t-RNA Synthetase from E.coli Complexed with TyrosineTyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine

Structural highlights

1x8x is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

SYY_ECOLI Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02006]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1x8x, resolution 2.00Å

Drag the structure with the mouse to rotate

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