2rhq: Difference between revisions

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[[Image:2rhq.jpg|left|200px]]


<!--
==PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies==
The line below this paragraph, containing "STRUCTURE_2rhq", creates the "Structure Box" on the page.
<StructureSection load='2rhq' size='340' side='right'caption='[[2rhq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2rhq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RHQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAX:1-{3-[(4-PYRIDIN-2-YLPIPERAZIN-1-YL)SULFONYL]PHENYL}-3-(1,3-THIAZOL-2-YL)UREA'>GAX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2rhq| PDB=2rhq |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhq OCA], [https://pdbe.org/2rhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rhq RCSB], [https://www.ebi.ac.uk/pdbsum/2rhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rhq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYFA_STAHJ SYFA_STAHJ]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/2rhq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rhq ConSurf].
<div style="clear:both"></div>


'''PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies'''
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2RHQ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHQ OCA].
[[Category: Large Structures]]
[[Category: Phenylalanine--tRNA ligase]]
[[Category: Protein complex]]
[[Category: Staphylococcus haemolyticus]]
[[Category: Staphylococcus haemolyticus]]
[[Category: Evdokimov, A G.]]
[[Category: Evdokimov AG]]
[[Category: Mekel, M.]]
[[Category: Mekel M]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Atp-binding]]
[[Category: Cytoplasm]]
[[Category: Heterotetramer]]
[[Category: Ligase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phenylalanine]]
[[Category: Protein biosynthesis]]
[[Category: Rna-binding]]
[[Category: Trna]]
[[Category: Trna-binding]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 16:55:37 2008''

Latest revision as of 12:22, 21 February 2024

PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studiesPheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies

Structural highlights

2rhq is a 2 chain structure with sequence from Staphylococcus haemolyticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SYFA_STAHJ

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2rhq, resolution 2.20Å

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OCA
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