2pkt: Difference between revisions

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New page: left|200px<br /> <applet load="2pkt" size="450" color="white" frame="true" align="right" spinBox="true" caption="2pkt, resolution 1.500Å" /> '''Crystal structure ...
 
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[[Image:2pkt.gif|left|200px]]<br />
<applet load="2pkt" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2pkt, resolution 1.500&Aring;" />
'''Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1'''<br />


==About this Structure==
==Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1==
2PKT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CA, CL, ACT, PG4 and PEG as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2PKT OCA].  
<StructureSection load='2pkt' size='340' side='right'caption='[[2pkt]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2pkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PKT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkt OCA], [https://pdbe.org/2pkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pkt RCSB], [https://www.ebi.ac.uk/pdbsum/2pkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDLI1_HUMAN PDLI1_HUMAN] Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pk/2pkt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pkt ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[PDZ and LIM domain protein|PDZ and LIM domain protein]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C.H.]]
[[Category: Arrowsmith CH]]
[[Category: Bray, J.]]
[[Category: Bray J]]
[[Category: Bunkoczi, G.]]
[[Category: Bunkoczi G]]
[[Category: Burgess-Brown, N.]]
[[Category: Burgess-Brown N]]
[[Category: Delft, F.von.]]
[[Category: Doyle DA]]
[[Category: Doyle, D.A.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Elkins J]]
[[Category: Elkins, J.]]
[[Category: Gileadi C]]
[[Category: Gileadi, C.]]
[[Category: Gileadi O]]
[[Category: Gileadi, O.]]
[[Category: Salah E]]
[[Category: SGC, Structural.Genomics.Consortium.]]
[[Category: Sundstrom M]]
[[Category: Salah, E.]]
[[Category: Ugochukwu E]]
[[Category: Sundstrom, M.]]
[[Category: Umeano C]]
[[Category: Ugochukwu, E.]]
[[Category: Uppenberg J]]
[[Category: Umeano, C.]]
[[Category: Weigelt J]]
[[Category: Uppenberg, J.]]
[[Category: Von Delft F]]
[[Category: Weigelt, J.]]
[[Category: ACT]]
[[Category: CA]]
[[Category: CL]]
[[Category: PEG]]
[[Category: PG4]]
[[Category: pdz domain]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:24:45 2007''

Latest revision as of 12:10, 21 February 2024

Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1

Structural highlights

2pkt is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDLI1_HUMAN Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pkt, resolution 1.50Å

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