8t1v: Difference between revisions
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<table><tr><td colspan='2'>[[8t1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T1V FirstGlance]. <br> | <table><tr><td colspan='2'>[[8t1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T1V FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XY8:3- | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XY8:3-[4-[[2,4-bis(fluoranyl)phenyl]methyl]piperazin-1-yl]-7-methyl-~{N}-propan-2-yl-pyrido[3,4-b]pyrazin-2-amine'>XY8</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t1v OCA], [https://pdbe.org/8t1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t1v RCSB], [https://www.ebi.ac.uk/pdbsum/8t1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t1v ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t1v OCA], [https://pdbe.org/8t1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t1v RCSB], [https://www.ebi.ac.uk/pdbsum/8t1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t1v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 09:38, 18 December 2024
Crystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3hCrystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3h
Structural highlights
FunctionC562_ECOLX Electron-transport protein of unknown function.GPR6_HUMAN Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). |
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