8t1v

Crystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3hCrystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3h

Structural highlights

8t1v is a 1 chain structure with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.6Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

C562_ECOLX Electron-transport protein of unknown function.GPR6_HUMAN Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).

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OCA