8fmb: Difference between revisions
New page: '''Unreleased structure''' The entry 8fmb is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Nodavirus RNA replication protein A polymerase domain, local refinement== | |||
<StructureSection load='8fmb' size='340' side='right'caption='[[8fmb]], [[Resolution|resolution]] 6.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8fmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Flock_House_virus Flock House virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FMB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fmb OCA], [https://pdbe.org/8fmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fmb RCSB], [https://www.ebi.ac.uk/pdbsum/8fmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fmb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RDRP_FHV RDRP_FHV] RNA-dependent RNA polymerase, which replicates the viral genome composed of 2 RNA segments, RNA1 and RNA2 (Probable). Does not need an exogenous primer (PubMed:24466277). Also possesses a terminal nucleotidyl transferase (TNTase) activity (PubMed:24466277). The TNTase catalyzes the addition of nucleotide to the 3'-end of plus- and minus-stranded RNAs, probably to repair the 3'-end nucleotide loss (PubMed:24466277). Forms the open necked connection to the cytosol of the virus-induced replication vesicles (PubMed:32690711, PubMed:36560715, PubMed:36693094). Mediates viral RNA1 recruitment (PubMed:17301137).<ref>PMID:17301137</ref> <ref>PMID:24466277</ref> <ref>PMID:32690711</ref> <ref>PMID:36560715</ref> <ref>PMID:36693094</ref> <ref>PMID:24466277</ref> | |||
==See Also== | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Flock House virus]] | |||
[[Category: Large Structures]] | |||
[[Category: Ahlquist P]] | |||
[[Category: Broadberry R]] | |||
[[Category: Grant T]] | |||
[[Category: Horswill M]] | |||
[[Category: Myers J]] | |||
[[Category: Pennington J]] | |||
[[Category: Rebolledo Viveros A]] | |||
[[Category: Unchwaniwala N]] | |||
[[Category: Zhan H]] | |||
[[Category: Den Boon J]] |