Intracrine signaling: Difference between revisions

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<StructureSection load='1bwx' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='1bwx' size='340' side='right' caption='Human parathyroid hormone fragment hPTH (1-39); [[1bwx]]' scene=''>
This is a default text for your page '''Intracrine signaling'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
Intracrine refers to a hormone that acts inside a cell, regulating intracellular events. In simple terms it means that the cell stimulates itself by cellular production of a factor that acts within the cell. [[Steroid hormones]] act through intracellular (mostly nuclear) receptors and, thus, may be considered to be intracrines.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
*[[Intracellular receptors]]
*[[Nuclear receptors]]


== Function ==
There are several protein/peptide hormones that are also intracrines. Notable examples that have been described in the references include:
 
*Peptides of the renin–angiotensin system: angiotensin II and angiotensin (1-7)
== Disease ==
*Fibroblast growth factor 2
 
*Parathyroid hormone-related protein
== Relevance ==
 
== Structural highlights ==
 
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


See also [[Signal transduction]].
</StructureSection>
</StructureSection>
== References ==
== References ==
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<references/>

Latest revision as of 14:37, 27 April 2022

Intracrine refers to a hormone that acts inside a cell, regulating intracellular events. In simple terms it means that the cell stimulates itself by cellular production of a factor that acts within the cell. Steroid hormones act through intracellular (mostly nuclear) receptors and, thus, may be considered to be intracrines.

There are several protein/peptide hormones that are also intracrines. Notable examples that have been described in the references include:

  • Peptides of the renin–angiotensin system: angiotensin II and angiotensin (1-7)
  • Fibroblast growth factor 2
  • Parathyroid hormone-related protein

See also Signal transduction.

Human parathyroid hormone fragment hPTH (1-39); 1bwx

Drag the structure with the mouse to rotate

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky