Pyruvate dehydrogenase 3D structures

3D structures of pyruvate dehydrogenase3D structures of pyruvate dehydrogenase

Updated on 04-October-2023

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• Pyruvate dehydrogenase E1 domain
  • 3exe - hPDH E1 α + β subunits - human
    
  • 1ni4, 6cfo – hPDH E1 α + β (mutant) subunits
    
  • 2ozl, 3exg, 3exh, 3exi, 6cer - hPDH E1 α (mutant) + β subunits
    
  • 3exf - hPDH E1 α (mutant) + β subunits + TDP
    
  • 1ik6 – PaPDH E1 β subunit – Pyrobaculum aerophilum
    
  • 1l8a, 2g25, 2g67, 2iea – EcPDH E1 – Escherichia coli
    
  • 3ey9, 3eya – EcPDH (cytochrome)
    
  • 2qta, 3lpl, 3lq2, 3lq4 - EcPDH E1 (mutant)
    
  • 2qtc - EcPDH E1 (mutant) + phosphonolactylthiamin diphosphate
    
  • 1rp7 - EcPDH E1 + inhibitor
    
  • 4qoy - EcPDH E1 + PDH E2
    
• Pyruvate dehydrogenase E2 domain see Dihydrolipoyl transacetylase and Dihydrolipoamide acetyltransferase
  • 7bgj, 7q5r – PDH E2 – Thermochaetoides thermophila – Cryo EM
    
• Pyruvate dehydrogenase E1+E2 domains
  • 1w85, 1w88 - BsPDH E1 α + β subunits + PDH E2 peripheral-subunit binding domain – Bacillus stearothermophilus
    
  • 3duf, 3dv0 - BsPDH E1 α + β subunits + PDH E2
    
  • 3dva - BsPDH E1 α (mutant) + β subunits + PDH E2
    
• Pyruvate dehydrogenase E3 domain
  • 6h60 – hPDH protein X – Cryo EM
    
  • 1zy8 – hPDH protein X + dihydrolipoyl dehydrogenase
    
  • 2f5z - hPDH protein X (mutant) + dihydrolipoyl dehydrogenase
    
  • 2f60 - hPDH protein X (mutant)
    
  • 2dnc, 2dne - hPDH protein X N terminal - NMR
    
  • 2g25 - hPDH protein X + phosphonolactylthiamin diphosphate
    
  • 2g28 - hPDH protein X (mutant) + phosphonolactylthiamin diphosphate
    
  • 2eq6 – TtPDH E3 – Thermus thermophilus
    
  • 4jdr – EcPDH E3
    
  • 1gjx – PDH E3 lipoyl domain – Neisseria meningitis – NMR
    
  • 6zlm – PDH protein X in PDH complex – Neurospora crassa - Cryo EM