2efg: Difference between revisions

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<StructureSection load='2efg' size='340' side='right'caption='[[2efg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2efg' size='340' side='right'caption='[[2efg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2efg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2efg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efg OCA], [https://pdbe.org/2efg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efg RCSB], [https://www.ebi.ac.uk/pdbsum/2efg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efg OCA], [https://pdbe.org/2efg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efg RCSB], [https://www.ebi.ac.uk/pdbsum/2efg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EFG_THETH EFG_THETH]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  
[https://www.uniprot.org/uniprot/EFG_THET8 EFG_THET8] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus HB8]]
[[Category: Czworkowski, J]]
[[Category: Czworkowski J]]
[[Category: Moore, P B]]
[[Category: Moore PB]]
[[Category: Steitz, T A]]
[[Category: Steitz TA]]
[[Category: Wang, J]]
[[Category: Wang J]]
[[Category: Elongation]]
[[Category: Elongation factor]]
[[Category: Gtp binding]]
[[Category: Gtpase]]
[[Category: Guanosine nucleotide binding]]
[[Category: Protein binding]]
[[Category: Protein synt factor]]
[[Category: Ribosome]]
[[Category: Translation]]
[[Category: Translocase]]

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