7w4t: Difference between revisions

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New page: '''Unreleased structure''' The entry 7w4t is ON HOLD Authors: Gupta, A.K., Gopal, B. Description: Structure of the M. tuberculosis HtrA S367A mutant at room-temperature [[Category: Unr...
 
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'''Unreleased structure'''


The entry 7w4t is ON HOLD
==Structure of the M. tuberculosis HtrA S367A mutant at room-temperature==
 
<StructureSection load='7w4t' size='340' side='right'caption='[[7w4t]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Gupta, A.K., Gopal, B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7w4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W4T FirstGlance]. <br>
Description: Structure of the M. tuberculosis HtrA S367A mutant at room-temperature
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w4t OCA], [https://pdbe.org/7w4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w4t RCSB], [https://www.ebi.ac.uk/pdbsum/7w4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w4t ProSAT]</span></td></tr>
[[Category: Gopal, B]]
</table>
[[Category: Gupta, A.K]]
== Function ==
[https://www.uniprot.org/uniprot/HTRA1_MYCTU HTRA1_MYCTU] Essential protein that may act as a regulatory protease that is conditionally activated upon appropriate environmental triggers.<ref>PMID:30511675</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Gopal B]]
[[Category: Gupta AK]]

Latest revision as of 00:24, 29 June 2023

Structure of the M. tuberculosis HtrA S367A mutant at room-temperatureStructure of the M. tuberculosis HtrA S367A mutant at room-temperature

Structural highlights

7w4t is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HTRA1_MYCTU Essential protein that may act as a regulatory protease that is conditionally activated upon appropriate environmental triggers.[1]

References

  1. ↑ Gupta AK, Behera D, Gopal B. The crystal structure of Mycobacterium tuberculosis high-temperature requirement A protein reveals an autoregulatory mechanism. Acta Crystallogr F Struct Biol Commun. 2018 Dec 1;74(Pt 12):803-809. doi:, 10.1107/S2053230X18016217. Epub 2018 Nov 29. PMID:30511675 doi:http://dx.doi.org/10.1107/S2053230X18016217

7w4t, resolution 2.20Å

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