7w4t

Structure of the M. tuberculosis HtrA S367A mutant at room-temperatureStructure of the M. tuberculosis HtrA S367A mutant at room-temperature

7w4t is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.2Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

HTRA1_MYCTU Essential protein that may act as a regulatory protease that is conditionally activated upon appropriate environmental triggers.^[1]

↑ Gupta AK, Behera D, Gopal B. The crystal structure of Mycobacterium tuberculosis high-temperature requirement A protein reveals an autoregulatory mechanism. Acta Crystallogr F Struct Biol Commun. 2018 Dec 1;74(Pt 12):803-809. doi:, 10.1107/S2053230X18016217. Epub 2018 Nov 29. PMID:30511675 doi:http://dx.doi.org/10.1107/S2053230X18016217