2d54: Difference between revisions

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<StructureSection load='2d54' size='340' side='right'caption='[[2d54]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2d54' size='340' side='right'caption='[[2d54]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2d54]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D54 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2d54]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D54 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d54 OCA], [https://pdbe.org/2d54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d54 RCSB], [https://www.ebi.ac.uk/pdbsum/2d54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d54 ProSAT], [https://www.topsan.org/Proteins/RSGI/2d54 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d54 OCA], [https://pdbe.org/2d54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d54 RCSB], [https://www.ebi.ac.uk/pdbsum/2d54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d54 ProSAT], [https://www.topsan.org/Proteins/RSGI/2d54 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8]] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.  
[https://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Methionine--tRNA ligase]]
[[Category: Thermus thermophilus]]
[[Category: Ishii, R]]
[[Category: Ishii R]]
[[Category: Konno, M]]
[[Category: Konno M]]
[[Category: Mori, Y]]
[[Category: Mori Y]]
[[Category: Structural genomic]]
[[Category: Takasaka R]]
[[Category: Takasaka, R]]
[[Category: Takeda R]]
[[Category: Takeda, R]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Class 1a aar]]
[[Category: Isomerase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rossmann fold]]
[[Category: Rsgi]]

Latest revision as of 11:24, 25 October 2023

Crystal Structure of Methionyl tRNA Synthetase Y225A Mutant from Thermus ThermophilusCrystal Structure of Methionyl tRNA Synthetase Y225A Mutant from Thermus Thermophilus

Structural highlights

2d54 is a 1 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

SYM_THET8 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2d54, resolution 2.00Å

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