7pl1: Difference between revisions

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New page: '''Unreleased structure''' The entry 7pl1 is ON HOLD Authors: Nai, F., Caflisch, A. Description: Crystal structure of human METTL1 bound to Sinefungin [[Category: Unreleased Structures...
 
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'''Unreleased structure'''


The entry 7pl1 is ON HOLD
==Crystal structure of human METTL1 bound to Sinefungin==
<StructureSection load='7pl1' size='340' side='right'caption='[[7pl1]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7pl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PL1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pl1 OCA], [https://pdbe.org/7pl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pl1 RCSB], [https://www.ebi.ac.uk/pdbsum/7pl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pl1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRMB_HUMAN TRMB_HUMAN] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<ref>PMID:12403464</ref>


Authors: Nai, F., Caflisch, A.
==See Also==
 
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
Description: Crystal structure of human METTL1 bound to Sinefungin
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Nai, F]]
__TOC__
[[Category: Caflisch, A]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Caflisch A]]
[[Category: Nai F]]

Latest revision as of 13:09, 16 August 2023

Crystal structure of human METTL1 bound to SinefunginCrystal structure of human METTL1 bound to Sinefungin

Structural highlights

7pl1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRMB_HUMAN Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.[1]

See Also

References

  1. ↑ Alexandrov A, Martzen MR, Phizicky EM. Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA. 2002 Oct;8(10):1253-66. PMID:12403464

7pl1, resolution 1.85Å

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