7mpy: Difference between revisions

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'''Unreleased structure'''


The entry 7mpy is ON HOLD
==Crystal structure of cytosolic HPPK-DHPS from A.thaliana==
<StructureSection load='7mpy' size='340' side='right'caption='[[7mpy]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7mpy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MPY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mpy OCA], [https://pdbe.org/7mpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mpy RCSB], [https://www.ebi.ac.uk/pdbsum/7mpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mpy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FOLC_ARATH FOLC_ARATH] Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis (PubMed:17289662). Plays a role in seed stress response and survival (PubMed:17289662, PubMed:21996493).<ref>PMID:17289662</ref> <ref>PMID:21996493</ref>


Authors:  
==See Also==
 
*[[HPPK 3D structures|HPPK 3D structures]]
Description:  
== References ==
[[Category: Unreleased Structures]]
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Bond CS]]
[[Category: Vadlamani G]]

Latest revision as of 19:18, 18 October 2023

Crystal structure of cytosolic HPPK-DHPS from A.thalianaCrystal structure of cytosolic HPPK-DHPS from A.thaliana

Structural highlights

7mpy is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FOLC_ARATH Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis (PubMed:17289662). Plays a role in seed stress response and survival (PubMed:17289662, PubMed:21996493).[1] [2]

See Also

References

  1. ↑ Storozhenko S, Navarrete O, Ravanel S, De Brouwer V, Chaerle P, Zhang GF, Bastien O, Lambert W, Rebeille F, Van Der Straeten D. Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response. J Biol Chem. 2007 Apr 6;282(14):10749-61. doi: 10.1074/jbc.M701158200. Epub 2007 , Feb 8. PMID:17289662 doi:http://dx.doi.org/10.1074/jbc.M701158200
  2. ↑ Navarrete O, Van Daele J, Stove C, Lambert W, Van Der Straeten D, Storozhenko S. A folate independent role for cytosolic HPPK/DHPS upon stress in Arabidopsis thaliana. Phytochemistry. 2012 Jan;73(1):23-33. doi: 10.1016/j.phytochem.2011.09.008. Epub , 2011 Oct 11. PMID:21996493 doi:http://dx.doi.org/10.1016/j.phytochem.2011.09.008

7mpy, resolution 2.30Å

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