Proteopedia

7mpy

Crystal structure of cytosolic HPPK-DHPS from A.thalianaCrystal structure of cytosolic HPPK-DHPS from A.thaliana

Structural highlights

7mpy is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FOLC_ARATH Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis (PubMed:17289662). Plays a role in seed stress response and survival (PubMed:17289662, PubMed:21996493).[1] [2]

See Also

References

  1. ↑ Storozhenko S, Navarrete O, Ravanel S, De Brouwer V, Chaerle P, Zhang GF, Bastien O, Lambert W, Rebeille F, Van Der Straeten D. Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response. J Biol Chem. 2007 Apr 6;282(14):10749-61. doi: 10.1074/jbc.M701158200. Epub 2007 , Feb 8. PMID:17289662 doi:http://dx.doi.org/10.1074/jbc.M701158200
  2. ↑ Navarrete O, Van Daele J, Stove C, Lambert W, Van Der Straeten D, Storozhenko S. A folate independent role for cytosolic HPPK/DHPS upon stress in Arabidopsis thaliana. Phytochemistry. 2012 Jan;73(1):23-33. doi: 10.1016/j.phytochem.2011.09.008. Epub , 2011 Oct 11. PMID:21996493 doi:http://dx.doi.org/10.1016/j.phytochem.2011.09.008

7mpy, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=7mpy&oldid=3914889"