P73: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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[[2xwc]] – hp73 DBD (mutant)<br /> | [[2xwc]] – hp73 DBD (mutant)<br /> | ||
[[2nb1]] - hp73 TD (mutant) + hp63 TD (mutant)<br /> | [[2nb1]] - hp73 TD (mutant) + hp63 TD (mutant)<br /> | ||
[[3vd0]], [[3vd1]], [[3vd2]], [[4g82]], [[4g83]], [[4guo]], [[4guq]], [[5kbd]] – hp73 DBD + DNA<br /> | [[3vd0]], [[3vd1]], [[3vd2]], [[4g82]], [[4g83]], [[4guo]], [[4guq]], [[5kbd]], [[7ezj]] – hp73 DBD + DNA<br /> | ||
[[4a63]] – hp73 DBD + apoptosis stimulating of p53 protein<br /> | [[4a63]] – hp73 DBD + apoptosis stimulating of p53 protein<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Latest revision as of 10:49, 21 August 2023
p73 is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis[1]. p73 has several variants differing in their C- or N-terminal. p73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). Structural highlights
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3D Structures of p733D Structures of p73
Updated on 21-August-2023
Domains - DNA-binding (DBD) 112-311; Tetramerization (TD) 351-398; C-terminal 439-506.
1cok – hp73 C terminal – human – NMR
2kby – hp73 TD – NMR
2wqi, 2wqj, 2wtt - hp73 TD
5hob, 5hoc - hp73 TD (mutant)
2xwc – hp73 DBD (mutant)
2nb1 - hp73 TD (mutant) + hp63 TD (mutant)
3vd0, 3vd1, 3vd2, 4g82, 4g83, 4guo, 4guq, 5kbd, 7ezj – hp73 DBD + DNA
4a63 – hp73 DBD + apoptosis stimulating of p53 protein