2ja2: Difference between revisions

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<StructureSection load='2ja2' size='340' side='right'caption='[[2ja2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2ja2' size='340' side='right'caption='[[2ja2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ja2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JA2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2JA2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ja2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JA2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate--tRNA_ligase Glutamate--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.17 6.1.1.17] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ja2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ja2 OCA], [http://pdbe.org/2ja2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ja2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ja2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ja2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ja2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ja2 OCA], [https://pdbe.org/2ja2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ja2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ja2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ja2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SYE_MYCTU SYE_MYCTU]] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).  
[https://www.uniprot.org/uniprot/SYE_MYCTU SYE_MYCTU] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glutamate--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Bartunik, H D]]
[[Category: Bartunik HD]]
[[Category: Bourenkov, G P]]
[[Category: Bourenkov GP]]
[[Category: Bruning, M]]
[[Category: Bruning M]]
[[Category: Shkolnaya, L A]]
[[Category: Shkolnaya LA]]
[[Category: Strizhov, N]]
[[Category: Strizhov N]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Atp-binding]]
[[Category: Ligase]]
[[Category: Non-discriminating glutamyl-trna aminoacylation]]
[[Category: Nucleotide-binding]]
[[Category: Protein biosynthesis]]

Latest revision as of 17:40, 13 December 2023

Mycobacterium tuberculosis glutamyl-tRNA synthetaseMycobacterium tuberculosis glutamyl-tRNA synthetase

Structural highlights

2ja2 is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.65Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SYE_MYCTU Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ja2, resolution 1.65Å

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