|
|
| (2 intermediate revisions by the same user not shown) |
| Line 13: |
Line 13: |
| The <scene name='59/591942/Cv/4'>2'3'-cGAMP binds at the lower part of the cleft between the N-lobe and C-lobe of CGAS</scene>.<ref>PMID:24462292</ref> | | The <scene name='59/591942/Cv/4'>2'3'-cGAMP binds at the lower part of the cleft between the N-lobe and C-lobe of CGAS</scene>.<ref>PMID:24462292</ref> |
|
| |
|
| ==3D structures of cyclic GMP-AMP synthase== | | ==3D structures of cyclic GMP-AMP structures== |
| [[Cyclic GMP-AMP synthase 3D synthase]] | | [[Cyclic GMP-AMP synthase 3D structures]] |
|
| |
|
| </StructureSection> | | </StructureSection> |
|
| |
| ==3D structures of cyclic GMP-AMP synthase==
| |
|
| |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| |
| {{#tree:id=OrganizedByTopic|openlevels=0|
| |
|
| |
| *cyclic GMP-AMP synthase
| |
|
| |
| **[[4k8v]] – mCGAS C terminal – mouse<br />
| |
| **[[4km5]], [[4mkp]], [[4lev]], [[4lew]], [[4o68]], [[4o69]] – hCGAS C terminal – human<br />
| |
| **[[4jlx]] – pCGAS C terminal – pig<br />
| |
| **[[4txy]], [[4xj1]] – VcCGAS – ''Vibrio cholerae''<br />
| |
| **[[4u0l]], [[4u0n]], [[5go3]] – VcCGAS (mutant)<br />
| |
|
| |
| *Cyclic GMP-AMP synthase complex
| |
|
| |
| **[[4k96]], [[4ley]], [[4lez]], [[4o6a]], [[5n6i]], [[5xzb]], [[5xze]], [[5xzg]] – mCGAS C terminal + DNA<br />
| |
| **[[4k97]] – mCGAS C terminal + DNA + ATP<br />
| |
| **[[4k98]], [[4k99]], [[4k9a]], [[4k9b]] – mCGAS C terminal + DNA + polynucleotide<br />
| |
| **[[4kb6]] – pCGAS C terminal + DNA + ATP + GTP <br />
| |
| **[[4jlz]] – pCGAS C terminal + UTP<br />
| |
| **[[4o67]] - hCGAS C terminal + cyclic GMP-AMP <br />
| |
| **[[5vdo]], [[5vdt]], [[5vdp]] - hCGAS C terminal + CGAMP <br />
| |
| **[[5vdq]] - hCGAS C terminal + GPAP <br />
| |
| **[[5vdr]] - hCGAS C terminal + CDIMP <br />
| |
| **[[5vds]] - hCGAS C terminal + CDUMP <br />
| |
| **[[6ct9]] - hCGAS C terminal (mutant) + DNA <br />
| |
| **[[6cta]] - hCGAS C terminal (mutant) + DNA + ATP<br />
| |
| **[[6nfg]], [[6nao]], [[5v8o]], [[5vdu]], [[5vdv]], [[5vdw]], [[6nfo]] - hCGAS C terminal + inhibitor <br />
| |
| **[[4txz]], [[4xj3]], [[4xj5]] – VcCGAS + GTP<br />
| |
| **[[4xj4]] – VcCGAS + ATP<br />
| |
| **[[4ty0]] – VcCGAS + PPPAPG<br />
| |
| **[[4u03]] – VcCGAS + GTP + 5MTHFGlu2<br />
| |
| **[[4u0m]] – VcCGAS (mutant) + GTP + ATP + 5MTHFGlu2<br />
| |
| }}
| |
|
| |
|
| |
|
| == References == | | == References == |