2rtz: Difference between revisions

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==Solution structure of MarkTX-7==
==Solution structure of MarkTX-7==
<StructureSection load='2rtz' size='340' side='right' caption='[[2rtz]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rtz' size='340' side='right'caption='[[2rtz]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rtz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RTZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rtz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RTZ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rtz OCA], [http://pdbe.org/2rtz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rtz RCSB], [http://www.ebi.ac.uk/pdbsum/2rtz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rtz ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rtz OCA], [https://pdbe.org/2rtz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rtz RCSB], [https://www.ebi.ac.uk/pdbsum/2rtz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rtz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KA261_MESMA KA261_MESMA] Recombinant toxin that reversibly inhibits the potassium current of mKv1.3/KCNA3 channel stably expressed in COS7 cells (IC(50)=150 nM) (PubMed:17624312). Also shows a weak inhibition on Kv1.2/KCNA2, Kv1.3/KCNA3 and TRPV1 channels (PubMed:29483648).<ref>PMID:17624312</ref> <ref>PMID:29483648</ref>


==See Also==
==See Also==
*[[Potassium channel toxin|Potassium channel toxin]]
*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buthus martensi]]
[[Category: Large Structures]]
[[Category: Ohki, S]]
[[Category: Mesobuthus martensii]]
[[Category: Umetsu, Y]]
[[Category: Ohki S]]
[[Category: Potassium channel blocker]]
[[Category: Umetsu Y]]
[[Category: Toxin]]

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