6b4j: Difference between revisions
Jump to navigation
Jump to search
New page: '''Unreleased structure''' The entry 6b4j is ON HOLD Authors: Description: Category: Unreleased Structures |
No edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
The entry | ==Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex== | ||
<StructureSection load='6b4j' size='340' side='right'caption='[[6b4j]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6b4j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B4J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b4j OCA], [https://pdbe.org/6b4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b4j RCSB], [https://www.ebi.ac.uk/pdbsum/6b4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b4j ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/GLE1_HUMAN GLE1_HUMAN] Lethal arthrogryposis - anterior horn cell disease;Lethal congenital contracture syndrome type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GLE1_HUMAN GLE1_HUMAN] Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).<ref>PMID:12668658</ref> <ref>PMID:16000379</ref> <ref>PMID:9618489</ref> | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cai SW]] | |||
[[Category: Correia AR]] | |||
[[Category: Hoelz A]] | |||
[[Category: Huber FM]] | |||
[[Category: Jette CA]] | |||
[[Category: Lin DH]] | |||
Latest revision as of 17:20, 13 March 2024
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complexCrystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex
Structural highlights
DiseaseGLE1_HUMAN Lethal arthrogryposis - anterior horn cell disease;Lethal congenital contracture syndrome type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. FunctionGLE1_HUMAN Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).[1] [2] [3] See AlsoReferences
|
| ||||||||||||||||||