5yed: Difference between revisions

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'''Unreleased structure'''


The entry 5yed is ON HOLD  until Paper Publication
==Crystal structure of LokiProfilin1==
 
<StructureSection load='5yed' size='340' side='right'caption='[[5yed]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5yed]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lokiarchaeum_sp._GC14_75 Lokiarchaeum sp. GC14_75]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YED FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yed OCA], [https://pdbe.org/5yed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yed RCSB], [https://www.ebi.ac.uk/pdbsum/5yed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yed ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PROF1_LOKSG PROF1_LOKSG] Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.<ref>PMID:30283132</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Lokiarchaeum sp. GC14_75]]
[[Category: Akil C]]
[[Category: Robinson RC]]

Latest revision as of 13:23, 27 March 2024

Crystal structure of LokiProfilin1Crystal structure of LokiProfilin1

Structural highlights

5yed is a 1 chain structure with sequence from Lokiarchaeum sp. GC14_75. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PROF1_LOKSG Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.[1]

References

  1. ↑ Akil C, Robinson RC. Genomes of Asgard archaea encode profilins that regulate actin. Nature. 2018 Oct 3. pii: 10.1038/s41586-018-0548-6. doi:, 10.1038/s41586-018-0548-6. PMID:30283132 doi:http://dx.doi.org/10.1038/s41586-018-0548-6

5yed, resolution 1.60Å

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