5y04: Difference between revisions

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'''Unreleased structure'''


The entry 5y04 is ON HOLD  until Paper Publication
==Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin==
<StructureSection load='5y04' size='340' side='right'caption='[[5y04]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5y04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y04 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y04 OCA], [https://pdbe.org/5y04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y04 RCSB], [https://www.ebi.ac.uk/pdbsum/5y04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y04 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VINC_MOUSE VINC_MOUSE] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity).[UniProtKB:P18206]<ref>PMID:7568093</ref>


Authors:  
==See Also==
 
*[[Catenin 3D structures|Catenin 3D structures]]
Description:  
*[[Vinculin 3D structures|Vinculin 3D structures]]
[[Category: Unreleased Structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Hakoshima T]]
[[Category: Hirano Y]]

Latest revision as of 13:21, 27 March 2024

Crystal Structure of the complex between the vinculin D1 domain and alphaE-cateninCrystal Structure of the complex between the vinculin D1 domain and alphaE-catenin

Structural highlights

5y04 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.85Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

VINC_MOUSE Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity).[UniProtKB:P18206][1]

See Also

References

  1. Coll JL, Ben-Ze'ev A, Ezzell RM, Rodriguez Fernandez JL, Baribault H, Oshima RG, Adamson ED. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9161-5. PMID:7568093

5y04, resolution 2.85Å

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OCA