5y04

Crystal Structure of the complex between the vinculin D1 domain and alphaE-cateninCrystal Structure of the complex between the vinculin D1 domain and alphaE-catenin

Structural highlights

5y04 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.85Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

VINC_MOUSE Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity).[UniProtKB:P18206]^[1]

References

↑ Coll JL, Ben-Ze'ev A, Ezzell RM, Rodriguez Fernandez JL, Baribault H, Oshima RG, Adamson ED. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9161-5. PMID:7568093

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OCA

[1] Coll JL, Ben-Ze'ev A, Ezzell RM, Rodriguez Fernandez JL, Baribault H, Oshima RG, Adamson ED. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9161-5. PMID:7568093

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5y04

Crystal Structure of the complex between the vinculin D1 domain and alphaE-cateninCrystal Structure of the complex between the vinculin D1 domain and alphaE-catenin

Structural highlights

Function

See Also

References

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5y04

Crystal Structure of the complex between the vinculin D1 domain and alphaE-cateninCrystal Structure of the complex between the vinculin D1 domain and alphaE-catenin

Structural highlights

Function

See Also

References

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