DnaA: Difference between revisions

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<StructureSection load='1j1v' size='350' side='right' scene='50/509255/Cv/1' caption='E. coli DnaA complex with DNA ([[1j1v]])'>
<StructureSection load='' size='350' side='right' scene='50/509255/Cv/1' caption='E. coli DnaA complex with DNA ([[1j1v]])'>


'''DnaA''' activates initiation of DNA replication in prokaryotes.  DnaA promotes the unwinding of the DNA helix.  The cellular concentration of DnaA determines the initiation of DNA replication.  Active DnaA is bound to ATP.  DnaA binds to DNA at a specific 9 base pair DnaA box in oriC (origin of replication sequence). <ref>PMID:17435790</ref>  
'''DnaA''' activates initiation of DNA replication in prokaryotes.  DnaA promotes the unwinding of the DNA helix.  The cellular concentration of DnaA determines the initiation of DNA replication.  Active DnaA is bound to ATP.  DnaA binds to DNA at a specific 9 base pair DnaA box in oriC (origin of replication sequence). <ref>PMID:17435790</ref>  
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[[2z4r]], [[2z4s]] - DnaA domain III – ''Thermotoga maritima''<br />
[[2z4r]], [[2z4s]] - DnaA domain III – ''Thermotoga maritima''<br />
[[2wp0]] - DnaA N terminal + HOBA – ''Helicobacter pylori''<br />
[[2wp0]] - DnaA N terminal + HOBA – ''Helicobacter pylori''<br />
[[3pvp]], [[3pvv]] - DnaA DNA binding domain + DNA – ''Mycobacterium tuberculosis''
[[3pvp]], [[3pvv]] - DnaA DNA binding domain + DNA – ''Mycobacterium tuberculosis''<br />
[[4tps]] - DnaA domain I + SirA – ''Bacillus subtilis''<br />
 
== References ==
== References ==
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[[Category:Topic Page]]

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Michal Harel, Alexander Berchansky, Joel L. Sussman