1a9c: Difference between revisions

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==GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP==
==GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP==
<StructureSection load='1a9c' size='340' side='right' caption='[[1a9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1a9c' size='340' side='right'caption='[[1a9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1a9c]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A9C FirstGlance]. <br>
<table><tr><td colspan='2'>[[1a9c]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A9C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a9c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a9c RCSB], [http://www.ebi.ac.uk/pdbsum/1a9c PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a9c OCA], [https://pdbe.org/1a9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a9c RCSB], [https://www.ebi.ac.uk/pdbsum/1a9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a9c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GCH1_ECOLI GCH1_ECOLI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a9/1a9c_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a9/1a9c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a9c ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cyclohydrolase|Cyclohydrolase]]
*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: GTP cyclohydrolase I]]
[[Category: Large Structures]]
[[Category: Auerbach, G]]
[[Category: Auerbach G]]
[[Category: Bacher, A]]
[[Category: Bacher A]]
[[Category: Bracher, A]]
[[Category: Bracher A]]
[[Category: Huber, R]]
[[Category: Huber R]]
[[Category: Nar, H]]
[[Category: Nar H]]
[[Category: Gtp]]
[[Category: Hydrolase]]
[[Category: Pterine synthesis]]
[[Category: Purine hydrolysis]]
[[Category: Tetrahydrobiopterin]]

Latest revision as of 09:28, 7 February 2024

GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTPGTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP

Structural highlights

1a9c is a 15 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GCH1_ECOLI

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1a9c, resolution 2.90Å

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