Cyclohydrolase 3D structures

3D structures of cyclohydrolase3D structures of cyclohydrolase

Updated on 17-February-2025

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• GTP cyclohydrolase I
  • 1fb1, 6z87 – hGCH I + Zn – human
    
  • 1gtp – EcGCH I – Escherichia coli
    
  • 5k9g – NgGCH IB + Zn – Neisseria gonorrhoeae
    
  • 3d2o – NgGCH IB + Mn
    
  • 1wm9 – TtGCH I + Zn – Thermus thermophilus
    
  • 4uqf – GCH I – Listeria monocytogenes
    
• GTP cyclohydrolase I complexes
  • 6z80 – hGCH I + GFRP + Zn + 8-oxo-GTP – Cryo EM
    
  • 6z85 – hGCH I + GFRP + Zn + dihydrobiopterin – Cryo EM
    
  • 6z86 – hGCH I + Zn + deaza-GTP
    
  • 6z88, 6z89 – hGCH I + Zn + inhibitor
    
  • 7alc – hGCH I + Zn + GFRP
    
  • 7alb, 7alq – hGCH I + Zn + deaza-GTP + GFRP
    
  • 7ala – hGCH I + Zn + inhibitor + GFRP
    
  • 1is7 – rGCH I + GFRP - rat
    
  • 1is8 – rGCH I + GFRP + Zn
    
  • 1wpl – rGCH I + GFRP + Zn + dihydrobiopterin
    
  • 1a8r, 1a9c, 1n3r, 1n3t, 1n3s – EcGCH I (mutant) + GTP
    
  • 4du6 – GCH I + GTP – Yersinia pseudotuberculosis
    
  • 1fbx – EcGCH I + Zn
    
  • 1wuq, 1wur – TtGCH I + Zn + 8-oxo-GTP
    
  • 5k95 – NgGCH 1B + Zn + 8-oxo-GTP
    
  • 8g6c, 8g8v – BpGCH 1B + cation – Burkholderia pseudomallei
    
  • 8tcc – BpGCH 1B + dehydrocostus lactone
    
• GTP cyclohydrolase II or UTP cyclohydrolase
  • 2bz1 – EcGCH II + Zn
    
  • 2bz0 – EcGCH II + Zn + phosphomethylphosphonic acid guanylate
    
  • 4rl4 – GCH II – Helicobacter pylori
    
  • 7ej3 – RwGCH II – Rhodococcus wratislaviensis
    
  • 7eev – RwGCH II + UTP
    
• GTP cyclohydrolase III
  • 2qv6 – GCH III + GTP + Ca – Methanocaldococcus jannaschii
    
• IMP cyclohydrolase
  • 2ntm – MtICH – Methanothermobacter thermoautotrophicus
    
  • 2ntk – MtICH + IMP
    
  • 2ntl – MtICH + AICAR
    
• Methenyltetrahydromethanopterin cyclohydrolase
  • 1qlm – MCH – Methanopyrus kandleri
    
  • 4fio – MCH – Methanobrevibacter ruminatium
    
  • 4gvr – AfMCH – Archaeoglobus fulgidus
    
  • 4gvq – AfMCH + tetrahydromethanopterin
    
  • 4gvs – AfMCH + N5-formyl-tetrahydromethanopterin
    
• Methylenetetrahydrofolate dehydrogenase/cyclohydrolase
  • 1a4i, 6ecr – hMCH + NADP
    
  • 1dig, 1dia, 1dib, 5tc4, 6ecp, 6ecq, 6s4a, 7ehj, 7qei, 9is9, 9isc, 9it3, 9it6, 9ita – hMCH + NADP + inhibitor
    
  • 6jib, 6jid, 6kg2, 7ehm, 7ehn, 7ehv – hMCH + inhibitor
    
  • 2c2x, 2c2y – MCH – Mycobacterium tuberculosis
    
  • 7vg4 – MeMCH – Methylorubrum extoquens
    
  • 7vg5 – MeMCH + THF
    
  • 8wfc – MCH – Porphyromonas gingivalis
    
• Phosphoribosyl-AMP cyclohydrolase
  • 1zps – MtPCH + Cd
    
  • 7bgm – MetPCH + Zn – Medicago truncatula
    
  • 7bgn – MetPCH + Zn + AMP